Saturday, March 19, 2022
| MATCHUP | TIME | NETWORK |
|---|---|---|
| 8 North Carolina @ 1 Baylor | 12:10 PM | CBS |
| 9 Creighton @ 1 Kansas | 2:40 PM | CBS |
| 11 Michigan @ 3 Tennesse | 5:15 PM | CBS |
| 12 Richmond @ 4 Providence | 6:10 PM | TNT |
| 5 Saint Mary’s @ 4 UCLA | 7:10 PM | TBS |
| 15 Saint Peter’s @ 7 Murray State | 7:45 PM | CBS |
| 12 New Mexico State @ 4 Arkansas | 8:40 PM | TNT |
| 9 Memphis @ 1 Gonzaga | 9:40 PM | TBS |
Sunday, March 20, 2022
| MATCHUP | TIME | NETWORK |
|---|---|---|
| 5 Houston @ 4 Illinois | 12:10 PM | CBS |
| 7 Ohio State @ 2 Villanova | 2:40 PM | CBS |
| 7 Michigan State @ 2 Duke | 5:15 PM | CBS |
| 11 Iowa State @ 3 Wisconsin | 6:10 PM | TNT |
| 11 Notre Dame @ 3 Texas Tech | 7:10 PM | TBS |
| 10 Miami @ 2 Auburn | 7:45 PM | truTV |
| 6 Texas @ 3 Purdue | 8:40 PM | TNT |
| 9 TCU @ 1 Arizona | 9:40 PM | TBS |
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